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Description

5-MeO-DiPT Also known as:

  • 1H-Indole-3-ethanamine, 5-methoxy-N,N-bis(1-methylethyl)-[ACD/Index Name]
  • 5-MeO-DIPT
  • 5-methoxy-N,N-diisopropyltryptamine
  • N,N-Diisopropyl-5-methoxytryptamine
  • N-Isopropyl-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-propanamin[German][ACD/IUPAC Name]
  • N-Isopropyl-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-propanamine[ACD/IUPAC Name]
  • N-Isopropyl-N-[2-(5-méthoxy-1H-indol-3-yl)éthyl]-2-propanamine[French][ACD/IUPAC Name]
  • N-Isopropyl-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]propan-2-amine
  • [2-(5-methoxy-1H-indol-3-yl)ethyl]bis(propan-2-yl)amine
  • '4021-34-5
  • 5-?METHOXY-?N,?N-?BIS(1-?METHYLETHYL)-?1H-?INDOLE-?3-?ETHANAMINE
  • 5-methoxy DiPT
  • 5-Methoxy-3-N,N-diisopropylaminoethylindole
  • 5-methoxy-N,N-bis(1-methylethyl)-1H-indole-3-ethanamine
  • BR-35049
  • diisopropyl-[2-(5-methoxy-1H-indol-3-yl)ethyl]amine
  • Diisopropyl-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine
  • FOXY
  • MFCD03840209
  • N-(1-methylethyl)-N-{2-[5-(methyloxy)-1H-indol-3-yl]ethyl}propan-2-amine
  • N,N-Diisopropyl-5-methoxy-tryptamine
  • N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-(propan-2-yl)propan-2-amine
  • N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-propan-2-ylpropan-2-amine
  • N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-propan-2-yl-propan-2-amine
  • N-{2-[5-(methyloxy)-1H-indol-3-yl]ethyl}-N-(propan-2-yl)propan-2-amine
  • N-2-(5-methoxy-1H-indole-3-yl)ethyl-N-(propane-2-yl)propane-2-amine[ACD/IUPAC Name]
  • N-isopropyl-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)propan-2-amine
  • PDSP1_000761
  • PDSP2_000749
  • TL8006514

5-methoxy-di isopropyl tryptamine, also known as ‘foxy’, a psychedelic tryptamine related to DMT, which distorts visual and audio perception. Reported to have a heavy body load at high doses, it behaves similarly to other drugs of its class.

Summary

It is related in structure to DiPT and 5-MeO-MiPT. The first human trials of 5-MeO-DiPT were undertaken by Alexander Shulgin in 1975. who would co-author and publish a paper detailing its synthesis and human psychopharmacology in 1981.

A summary of the synthesis and reports of human use is included in Shulgin’s 1997 book TiHKAL (“Tryptamines I Have Known And Loved”). Anecdotal reports characterize the effects of this compound as highly stimulating and mildly entactogenic, lacking in typical psychedelic visual distortions. Many users report strong physical and tactile effects that serve to enhance libido and sexual pleasure.

Many users note an unpleasant body load accompanies higher dosages. Some users also report sound distortion, which is also noted with the related compound, DiPT. Very little is known about the pharmacological properties, metabolism and toxicity of 5-MeO-DiPT.

It is relatively obscure and has a limited history of human use. It has been sold online as a research chemical. It is highly advised to use harm reduction practices if using this substance.

Chemistry

5-MeO-DiPT

5-MeO-DiPT

Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain.

5-MeO-DiPT is substituted at R5 of its indole heterocycle with a methoxy (MeO) functional group CH3O−; it also contains two isopropyl chains bound to the terminal amine RN of its tryptamine backbone (DiPT). 5-MeO-DiPT is the N-substituted diisopropyl homolog of 5-MeO-MiPT.

Common Name5-MeO-DIPT
Systematic name5-MeO-DIPT
FormulaC_{17}H_{26}N_{2}O
SMILESCC(C)N(CCc1c[nH]c2c1cc(cc2)OC)C(C)C
Std. InChiInChI=1S/C17H26N2O/c1-12(2)19(13(3)4)9-8-14-11-18-17-7-6-15(20-5)10-16(14)17/h6-7,10-13,18H,8-9H2,1-5H3
Std. InChiKeyDNBPMBJFRRVTSJ-UHFFFAOYSA-N
Avg. Mass274.4011 Da
Molecular Weight274.4011
Monoisotopic Mass274.204498 Da
Nominal Mass274
ChemSpider ID133247

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Dose Chart

Oral
Threshold3mg
Light5-10mg
Common8-15mg
Strong15-25mg+

Duration Chart

5-MeO-DiPT Duration Data
Onset20-40 minutes
Duration4-8 hours
After-effects2-3 hours

Auditory Effects

Psychological Effects

Pharmacological Effects

5-MeO-DiPT’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist, although additional mechanisms of action such as MAOIs may also be involved. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Physical Effects

Sensory Effects

  • Synaesthesia - In its fullest manifestation, this is a very rare and non-reproducible effect. Increasing the dosage can increase the likelihood of this occurring, but seems to only be a prominent part of the experience among those who are already predisposed to synaesthetic states.

Subjective Effects

Visual Effects

Enhancements

Distortions

Geometry

Hallucinatory states

Legal Status

  • Brazil: Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.
  • China: 5-MeO-DiPT is illegal in China.
  • Denmark: 5-MeO-DiPT is illegal in Denmark.
  • Germany: 5-MeO-DiPT is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of October 10, 2000. It is illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license.
  • Greece: 5-MeO-DiPT is illegal in Greece.
  • Japan: 5-MeO-DiPT is illegal in Japan.
  • Latvia: 5-MeO-DiPT is illegal in Latvia.
  • New Zealand: 5-MeO-DiPT can be considered an analogue of DMT, which makes it a Class C controlled drug in New Zealand.
  • Singapore: 5-MeO-DiPT is illegal in Singapore.
  • Sweden: 5-MeO-DiPT is illegal in Sweden.
  • United Kingdom: 5-MeO-DiPT is a Class A drug in the UK as it is an ether of the drug 5-HO-DiPT, which is a Class A drug as a result of the tryptamine catch-all clause.
  • United States: 5-MeO-DiPT is a Schedule 1 controlled substance.
  • Sources

    References

    1. Shulgin, Alexander. "Pharmacology Lab Notes #1". Lafayette, CA. (1960-1976). p176 (Erowid.org) | https://erowid.org/library/books_online/shulgin_labbooks/shulgin_labbook1_searchable.pdf
    2. Shulgin, AT; Carter, MF. N,N-diisopropyltryptamine (DIPT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT). Two orally active tryptamine analogs with CNS activity. Commun. Psychopharmacol., 1 Jan 1981, 4 (5), 363–369 | https://www.ncbi.nlm.nih.gov/pubmed/6949674
    3. https://erowid.org/library/books_online/tihkal/tihkal.shtml
    4. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain (ScienceDirect) | http://www.sciencedirect.com/science/article/pii/S0014299906013811 / https://www.ncbi.nlm.nih.gov/pubmed/17223101
    5. https://www.ncbi.nlm.nih.gov/pubmed/27461536
    6. R. Baselt, Disposition of Toxic Drugs and Chemicals in Man, 8th edition, Biomedical Publications, Foster City, CA, 2008, pp. 975-976.
    7. https://www.ncbi.nlm.nih.gov/pubmed/23244432
    8. https://www.ncbi.nlm.nih.gov/pubmed/3709792
    9. http://portal.anvisa.gov.br/documents/10181/3115436/(1)RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7
    10. http://www.sfda.gov.cn/WS01/CL0056/130753.html
    11. "Vierzehnte Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften" (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
    12. "Anlage I BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    13. "§ 29 BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    14. http://www.legislation.govt.nz/act/public/1975/0116/latest/whole.html#DLM436576
    15. http://www.notisum.se/rnp/sls/sfs/20040696.pdf
    16. Misuse of Drugs Act 1971 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I/paragraph/3
    17. Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e

    Information made possible with:

    1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
    2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
    3. PubChem National Center for Bio Informatics
    4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
    5. Wikipedia

    Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.

    Data is constantly updated so please check back later to see if there is any more available information on this substance.