4-AcO-DET

4-AcO-DALT

4-AcO-DALT

Psychoactive Research chemicals are new synthetic substances that are structurally similar to the original drug, while being functional analogs. Research on the effects of, and treatment for, abuse of these drugs is limited due to the fact that they’re fairly new and have avoided mainstream notice. Research chemicals do not have a lot of human consumption data, and thus harm-reduction and special care should be taken if choosing to ingest them.

Psychedelics are drugs which cause profound changes in a one’s perceptions of reality, otherwise known as hallucinations. While under the influence of hallucinogens, users might see images, hear sounds or feel sensations. These chemicals offer some of the most intense psychological experiences and care should be taken when ingesting them.

Experimental drugs have extremely limited human consumption data. There is not enough reliable information about this substance. This is most likely because the substance is is not very old. Information on these substances is limite and incomplete. Please be cautioned. Always practice harm reduction.

Disclaimer: Psychedelic drugs offer some of the most power and intense psychological experiences. Additionally these substances are illegal in many places. We understand that even though these substances are illegal, their use occurs frequently. We do not condone breaking of the law. By providing accurate information about these substances, we encourage the user to make responsible decisions and practice harm reduction.

Read the full disclaimer here.

Practice Harm Reduction. Proceed with Caution.

Description

4-AcO-DET

Also known as:

Rare drug that is of the tryptamine family, can be comparable to Psilocybin. Expected to quickly hydrolyzed into the free phenolic 4-HO-DET.

Summary

There is very little information on the human pharmacology or toxicity of 4-AcO-DET, although analytical methods have been developed for its detection. Today it is either used recreationally as a designer drug or as an entheogenic compound and is typically acquired through the use of online research chemical vendors. It remains relatively rare and has very little documented history of human usage.

4-AcO-DET is the acetylated form of 4-HO-DET (also known as ethocin) and is a higher homolog of 4-AcO-DMT and 4-AcO-MET. Like the aforementioned compounds, it is commonly hypothesized to act principally as a prodrug for their respective hydrolyzed counterparts (e. g.

4-HO-DMT, 4-HO-MET and 4-HO-DET). In theory, they would become inactive until they are deacetylated in the body, although there is on-going discussion as to whether they might display their own intrinsic activity.

History

Chemistry

4-AcO-DALT

4-AcO-DALT

Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain.

4-AcO-DET is substituted at R4 of its indole heterocycle with an acetoxy (AcO) functional group CH3COO−.

It also contains isopropyl and methyl chains bound to the terminal amine RN of its tryptamine backbone (DET). 4-AcO-DET is the N-substituted diethyl homolog of 4-HO-DMT (psilocin).

4-AcO-DET is the acetate ester analog of DET and the N-substituted diethyl analog of 4-AcO-DMT.

Common Name4-AcO-DALT
Systematic name4-AcO-DALT
FormulaC_{18}H_{22}N_{2}O_{2}
SMILESCC(=O)Oc1cccc2c1c(c[nH]2)CCN(CC=C)CC=C
Std. InChiInChI=1S/C18H22N2O2/c1-4-10-20(11-5-2)12-9-15-13-19-16-7-6-8-17(18(15)16)22-14(3)21/h4-8,13,19H,1-2,9-12H2,3H3
Std. InChiKeyWRHFDIBXZYYCHO-UHFFFAOYSA-N
Avg. Mass298.3795 Da
Molecular Weight298.3795
Monoisotopic Mass298.168121 Da
Nominal Mass298
ChemSpider ID32078886

Subscribe for the latest updates

Dosing Guide

Oral
Threshold2-5mg
Light5-15mg
Common10-15mg
Strong15-30mg

Duration

Oral
Onset15-60 minutes
Duration2-6 hours
After-effects1-6 hours

Interactions and Synergies

There are no existing interaction or synergy data for this drug.

General Information

Experiences
Oral
Vaporization
Come up
Dosage
Effects
After Effects
Avoid
Warning
Risks
Test Kits
Marguis Test Result
Tolerance
Detection
Half-life
Advice
Note
Note 2:
Note 3:

Effects

Pharmacological Effects

Like with most psychedelic tryptamines, 4-AcO-DET is thought to act principally as a 5-HT2A partial agonist. The psychedelic effects are believed to come from 4-AcO-DET’s binding efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective Effects

Disclaimer: The effects listed below are cited from the Subjective Effect Index (SEI), which relies on assorted anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be taken with a healthy amount of skepticism. It is worth noting that these effects will not necessarily occur in a consistent or reliable manner, although higher doses (common+) are more likely to induce the full spectrum of reported effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.

Physical Effects

Psychological Effects

Much like its hydroxylated counterpart 4-HO-DET, the cognitive effects of 4-AcO-DET are described by many as being relatively complex and unpredictable in style when compared to other commonly used psychedelics such as LSD or 2C-B which tend to be energetic and stimulating. It contains a notable number of typical and unique psychedelic cognitive effects. The most prominent of these typical effects generally include:

Visual Effects

Enhancements

Distortions

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of LSD, 2C-B or 2C-E than that of 4-AcO-DMT and ayahuasca. It can be comprehensively described through its variations as intricate in complexity, abstract in form, synthetic in style, structured in organization, brightly lit and multicoloured in scheme, glossy in shading, soft in edges, large in size, slow in speed, smooth in motion, rounded in corners, non-immersive in depth and consistent in intensity. The visuals have a very "artificial" feel to them and at higher dosages are significantly more likely to result in states of level 8A visual geometry over level 8B.

Hallucinatory states

4-AcO-DET and its various other forms can produce a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. These effects generally include:

Auditory Effects

Sensory Effects

Transpersonal Effects

Legal Status

Due to its relative obscurity, the possession and sale of 4-AcO-DET is unscheduled in most countries.

  • Germany: Because it is an ester of DET, 4-AcO-DET is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of January 24, 1974. It is illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license.
  • United Kingdom: 4-AcO-DET is a Class A drug in the UK as it is an ester of the drug 4-HO-DET., which is a Class A drug as a result of the tryptamine catch-all clause.
  • United States: 4-AcO-DET is unscheduled in the United States. It may be considered an analogue of psilocin (4-HO-DMT) which is a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.

  • References

    1. http://www.sciencedirect.com/science/article/pii/S0039914008005808
    2. http://link.springer.com/article/10.1007/s00044-011-9794-y
    3. 4-Acetoxy-DET - PubChem | https://pubchem.ncbi.nlm.nih.gov/compound/3-_2-_Diethylamino_ethyl_-1H-indol-4-yl_acetate#section=Top
    4. Talaie, H.; Panahandeh, R.; Fayaznouri, M. R.; Asadi, Z.; Abdollahi, M. (2009). "Dose-independent occurrence of seizure with tramadol". Journal of Medical Toxicology. 5 (2): 63–67. :10.1007/BF03161089.  1556-9039.
    5. "Sechste Verordnung über die den Betäubungsmitteln gleichgestellten Stoffe" (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
    6. "Anlage I BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    7. "§ 29 BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    8. Misuse of Drugs Act 1971 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I/paragraph/3
    9. Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e

    Sources

    Information made possible with:

    1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
    2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
    3. PubChem National Center for Bio Informatics
    4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
    5. Wikipedia

    Additional APIs were used to construct this information. Thanks for ChemSpider, NCBI, PubChem etc.

    Data is constantly updated so please check back later to see if there is any more available information on this substance.