Psychedelic Research Chemicals or RC Chems are new synthetic substances which are structurally similar to the original drug, while being functional analogs. Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history.

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This is an Experimental Substance with little data. This is most likely because the substance is is not very old. Information is limite and incomplete.

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Description

4-HO-DPT Also known as:

  • 1H-Indol-4-ol, 3-[2-(dipropylamino)ethyl]-[ACD/Index Name]
  • 3-[2-(Dipropylamino)ethyl]-1H-indol-4-ol[ACD/IUPAC Name]
  • 3-[2-(Dipropylamino)ethyl]-1H-indol-4-ol[German][ACD/IUPAC Name]
  • 3-[2-(Dipropylamino)éthyl]-1H-indol-4-ol[French][ACD/IUPAC Name]
  • DIPROPYL-4-HYDROXYTRYPTAMINE
  • 4-HO-DPT
  • 4-hydroxy DPT
  • 4-Hydroxydipropyltryptamine
  • 4-Hydroxy-N,N-dipropyltryptamine
  • Deprocin

A psychedelic hallucinogenic first synthesized by alexander shulgin. At light doses it causes enhanced cognition and appreciation for things like art and music while high doses cause visuals. The drug is known to cause a bodyload.

Summary

Alexander Shulgin first synthesized 4-HO-DPT and documented it in his book TiHKAL (Tryptamines I Have Known and Loved). It is the 4-hydroxyl analog of DPT. Today it is either used recreationally or as an entheogenic compound and is typically acquired through the use of online research chemical vendors.

Due to the difficulty of its synthesis, it remains relatively uncommon even for a substituted tryptamine and has very little history of human usage.

Chemistry

4-HO-DPT

4-HO-DPT

Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain.

4-HO-DPT is substituted at R4 of its indole heterocycle with a hydroxyl functional group OH−.

It also contains two propyl chains bound to the terminal amine RN of its tryptamine backbone (DPT). 4-HO-DPT is a 4-hydroxy analog of 4-AcO-DPT and the N-substituted dipropyl homolog of psilocin (4-HO-DMT).

Common NameDIPROPYL-4-HYDROXYTRYPTAMINE
Systematic nameDIPROPYL-4-HYDROXYTRYPTAMINE
FormulaC_{16}H_{24}N_{2}O
SMILESCCCN(CCC)CCc1c[nH]c2c1c(ccc2)O
Std. InChiInChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-12-17-14-6-5-7-15(19)16(13)14/h5-7,12,17,19H,3-4,8-11H2,1-2H3
Std. InChiKeyMZLRMPTVOVJXLW-UHFFFAOYSA-N
Avg. Mass260.3746 Da
Molecular Weight260.3746
Monoisotopic Mass260.188873 Da
Nominal Mass260
ChemSpider ID10579817

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Dose Chart

Oral
Light25-50mg
Moderate50-75mg
Strong75-100mg
Heavy100mg

Duration Chart

Insufflated
Onset10-20 minutes
Duration2-4 hours

Auditory Effects

Psychological Effects

Pharmacological Effects

Like with most psychedelic tryptamines, 4-HO-DPT is thought to act principally as a 5-HT2A partial agonist. The psychedelic effects are believed to come from 4-HO-DPT’s binding efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Physical Effects

Subjective Effects

Disclaimer: The effects listed below are cited from the Subjective Effect Index (SEI), which relies on assorted anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be taken with a healthy amount of skepticism. It is worth noting that these effects will not necessarily occur in a consistent or reliable manner, although higher doses (common+) are more likely to induce the full spectrum of reported effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.

Visual Effects

Enhancements

Suppressions

Distortions

Geometry

Hallucinatory states

Legal Status

Due to its relative obscurity, 4-HO-DPT is unscheduled in most countries.

  • Germany: 4-HO-DPT is controlled under the NpSG (New Psychoactive Substances Act) as of July 18, 2019. Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.
  • Sweden: 4-HO-DPT is classified as a "dangerous substance", which means it requires a special permit to buy or sell. It is, however, not yet classified as a drug.
  • United Kingdom: 4-HO-DPT is a Class A drug in the United Kingdom as a result of the tryptamine catch-all clause.
  • United States: 4-HO-DPT is unscheduled in the United States. It may be considered an analogue of psilocin (which is a Schedule I drug under the Controlled Substances Act). As such, the sale for human consumption or could be prosecuted as crimes under the Federal Analogue Act.
  • Sources

    References

    1. https://www.erowid.org/library/books_online/tihkal/tihkal20.shtml
    2. Talaie, H.; Panahandeh, R.; Fayaznouri, M. R.; Asadi, Z.; Abdollahi, M. (2009). "Dose-independent occurrence of seizure with tramadol". Journal of Medical Toxicology. 5 (2): 63–67. :10.1007/BF03161089.  1556-9039.
    3. "Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes" (PDF) (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
    4. "Anlage NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    5. "§ 4 NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    6. https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2018/februari/tio-nya-amnen-kan-klassas-som-narkotika-eller-halsofarlig-vara/
    7. Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e

    Information made possible with:

    1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
    2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
    3. PubChem National Center for Bio Informatics
    4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
    5. Wikipedia

    Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.

    Data is constantly updated so please check back later to see if there is any more available information on this substance.