Psychedelic Research Chemicals or RC Chems are new synthetic substances which are structurally similar to the original drug, while being functional analogs. Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history.

Psychedelics are substances (natural or laboratory made) which cause profound changes in a one’s perceptions of reality. While under the influence of hallucinogens, users might hallcuniate visually and auditorily.

Disclaimer: Psychedelic drugs offer some of the most powerful and intense psychological experiences. Additionally these substances are illegal in many places. We understand that even though these substances are illegal, their use occurs frequently. We do not condone breaking of the law. By providing accurate information about these substances, we encourage the user to make responsible decisions and practice harm reduction.

Read the full disclaimer here.

Description

4-AcO-DiPT Also known as:

  • 1H-Indol-6-ol, 3-[2-[bis(1-methylethyl)amino]ethyl]-, acetate (ester)[ACD/Index Name]
  • 3-[2-(Diisopropylamino)ethyl]-1H-indol-6-yl acetate[ACD/IUPAC Name]
  • 3-[2-(Diisopropylamino)ethyl]-1H-indol-6-yl-acetat[German][ACD/IUPAC Name]
  • Acétate de 3-[2-(diisopropylamino)éthyl]-1H-indol-6-yle[French][ACD/IUPAC Name]
  • 3-(2-di(propan-2-yl)aminethyl)-1H-indol-4-yl-acetate[ACD/IUPAC Name]
  • 4-Acetoxy-diisopropyltryptamine
  • 4-acetoxy-n,n-diisopropyltryptamine
  • 4-AcO-DIPT

An uncommon psychedelic tryptamine with a short history of human use, also known as Ipracetin. Possibly first synthesised by Alexander Shulgin. Some reports of heavy nausea, with effects comparable to 2c-b and mushrooms.

Summary

It has been described in early online reports as being only vaguely similar to structurally-related tryptamine substances such as psilocin or 4-AcO-DMT but with the disinhibiting, physically euphoric and libidinous signature of psychedelics like 5-MeO-DiPT, and an atypically short duration of around 3 - 4 hours. It has since been reported to be slightly longer lasting and mildly less potent than 4-HO-DiPT (also known as Iprocin) with an active dose reported as between 15 and 40 mg. 4-AcO-DiPT is primarily thought to act as a prodrug to 4-HO-DiPT, a substance which Alexander Shulgin comments on in his book TiHKAL.

In it he writes that he “truly doubt(s) that there is another psychedelic drug, anywhere, that can match this one for speed, for intensity, for brevity, and sensitive to dose, at least one that is active orally. " Anecdotal reports dating from at least 1999 reveals that these properties are largely preserved with 4-AcO-DiPT, with the exception of a less rapid and potentially jarring onset, slightly extended duration and decreased physical side-effects from the excessive stimulation and restlessness that 4-HO-DiPT is commonly reported to produce, making it a more comfortable experience overall. Today, 4-AcO-DiPT is rarely able to be acquired on the consumer market and when it is, is almost exclusively distributed as a gray-area research chemical online for recreational and proclaimed entheogenic purposes.

It is an example of the early wave of psychedelic research chemical that were explored following the wake of its initial synthesis and documentation in TiHKAL, before the emergence of an easily-accessible network of online research chemical vendors during the early 2000s. Very little data exists about the pharmacological properties, metabolism, and toxicity of 4-AcO-DiPT. Users are advised to proceed with caution when choosing to use this substance.

Chemistry

Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain.

4-AcO-DiPT is substituted at R4 of its indole heterocycle with an acetoxy (-AcO) functional group CH3COO−.

It also contains two diisopropyl chains bound to the terminal amine RN of its base tryptamine backbone (i.e.

DiPT). Structurally, 4-AcO-DiPT is the the acetate ester analog of DiPT, N-substituted isopropyl homolog of 4-HO-DMT (Psilocin), and the N-substituted diisopropyl analog of 4-AcO-DMT.

Common Name3-[2-(Diisopropylamino)ethyl]-1H-indol-6-yl acetate
Systematic name3-[2-(Diisopropylamino)ethyl]-1H-indol-6-yl acetate
FormulaC_{18}H_{26}N_{2}O_{2}
SMILESCC(C)N(CCc1c[nH]c2c1ccc(c2)OC(=O)C)C(C)C
Std. InChiInChI=1S/C18H26N2O2/c1-12(2)20(13(3)4)9-8-15-11-19-18-10-16(22-14(5)21)6-7-17(15)18/h6-7,10-13,19H,8-9H2,1-5H3
Std. InChiKeyGGRGBWNWGIREBY-UHFFFAOYSA-N
Avg. Mass302.4112 Da
Molecular Weight302.4112
Monoisotopic Mass302.199432 Da
Nominal Mass302
ChemSpider ID29760176

Become an Exclusive Member For Free

Become a member now, sign up, and get free updates, news articles, and the latest happenings in the Psychedelic World.

Dose Chart

Oral
Threshold3-5mg
Light5-10mg
Common10-20mg
Strong20-35mg

Duration Chart

4-AcO-DiPT Duration Data
Onset20-90 minutes
Duration2-5 hours
After-effects1-8 hours

Legal Status

Sources

References

  1. Erowid. (n.d.). Erowid 4-Acetoxy-DiPT Vault. Retrieved from https://erowid.org/chemicals/4_acetoxy_dipt/4_acetoxy_dipt.shtml
  2. Erowid. (1999, November). Erowid 4-Acetoxy-DiPT Vaults: Primer. Retrieved from https://www.erowid.org/chemicals/4_acetoxy_dipt/4_acetoxy_dipt_primer.shtml
  3. Shulgin, A., & Shulgin, A. (1991). Erowid Online Books: "TIHKAL" - #17. 4-HO-DIPT. Retrieved May 2, 2017.
  4. National Center for Biotechnology Information. PubChem Compound Database; CID=24801868, https://pubchem.ncbi.nlm.nih.gov/compound/24801868 (accessed May 2, 2017).
  5. Talaie, H.; Panahandeh, R.; Fayaznouri, M. R.; Asadi, Z.; Abdollahi, M. (2009). "Dose-independent occurrence of seizure with tramadol". Journal of Medical Toxicology. 5 (2): 63–67. :10.1007/BF03161089.  1556-9039.
  6. https://www.retsinformation.dk/Forms/R0710.aspx?id=137169
  7. "Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes" (PDF) (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
  8. "Anlage NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
  9. "§ 4 NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
  10. ホーム > 政策について > 分野別の政策一覧 > 健康・医療 > 医薬品・医療機器 > 薬物乱用防止に関する情報 | http://www.mhlw.go.jp/bunya/iyakuhin/yakubuturanyou/scheduled-drug/list.html
  11. Svensk författningssamling | http://www.notisum.se/rnp/sls/sfs/20050026.pdf
  12. Misuse of Drugs Act 1971 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I/paragraph/3
  13. Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e

Information made possible with:

  1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
  2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
  3. PubChem National Center for Bio Informatics
  4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
  5. Wikipedia

Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.

Data is constantly updated so please check back later to see if there is any more available information on this substance.