I am on anti-depressents. Is it okay to take psychedelics?
Antidepressants affect the serotonin system, just as most classic psychedelics do. It is a well-known fact that psychedelics and antidepressants do not mix well. It is best to avoid taking them together. How dangerous the combination can depend on the specific type of antidepressant, it’s dosage level, and which psychedelic it was combined with and in what dosage.
Psychedelics are unpredictable. Mixing them with drugs that also affect the serotonin system can pose unforeseeable complications and could potentially be dangerous. Lithium for example when combined with LSD prolongs the effects can be potentially very dangerous.
In short, it is not a good idea to mix the two types of drugs together.