Psychedelics are substances (natural or laboratory made) which cause profound changes in a one’s perceptions of reality. While under the influence of hallucinogens, users might hallcuniate visually and auditorily.

This is a commonly used substance with well known effects, but that does not guarantee the substance will be safe. The safety profile has been established based on usage data commonly reported by others.

Disclaimer: Psychedelic drugs offer some of the most powerful and intense psychological experiences. Additionally these substances are illegal in many places. We understand that even though these substances are illegal, their use occurs frequently. We do not condone breaking of the law. By providing accurate information about these substances, we encourage the user to make responsible decisions and practice harm reduction.

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Peyote Also known as:

  • 2-(3,4,5-Trimethoxyphenyl)ethanamin[German][ACD/IUPAC Name]
  • 2-(3,4,5-Trimethoxyphenyl)ethanamine[ACD/IUPAC Name]
  • 2-(3,4,5-Triméthoxyphényl)éthanamine[French][ACD/IUPAC Name]
  • 2-(3,4,5-Trimethoxyphenyl)ethylamine
  • 3,4,5-Trimethoxy-b-phenethylamine
  • Benzeneethanamine, 3,4,5-trimethoxy-[ACD/Index Name]
  • 1-amino-2-(3,4,5-trimethoxyphenyl)ethane
  • 3,4, 5-Trimethoxyphenethylamine
  • 3,4,5-Triaminopyridine
  • 3,4,5-Trimethoxybenzeneethanamine
  • 3,4,5-trimethoxyphenethylamine
  • 3,4,5-Trimethoxy-phenylethylamine
  • Ethane, 1-amino-2-(3, 4,5-trimethoxyphenyl)-
  • Ethane, 1-amino-2-(3,4,5-trimethoxyphenyl)-
  • Mescalin
  • Mescalin [German]
  • mescalina
  • Mescline
  • Meskalin
  • Mezcalin
  • mezcalina
  • Mezcaline
  • Mezcline
  • MFCD00128240[MDL number]
  • Phenethylamine, 3,4,5-trimethoxy-
  • Tmpea
  • WLN: Z2R CO1 DO1 EO1
  • β-D

Peyote is a small, spineless cactus that contains mescaline as its primary active chemical. It has a long history of use among the natives of northern Mexico and SW United States.


Native North Americans are likely to have used peyote, often for spiritual purposes, for at least 5,500 years.


Common NameMescaline
Systematic nameMescaline
Std. InChiInChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
Avg. Mass211.2576 Da
Molecular Weight211.2576
Monoisotopic Mass211.12085 Da
Nominal Mass211
ChemSpider ID3934

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Dose Chart


Duration Chart

Peyote Duration Data
Onset60-120 minutes
After-effects6-8 hours

Legal Status



  1. Lophophora williamsii |
  2. Lophophora diffusa |
  4. El-Seedi HR, De Smet PA, Beck O, Possnert G, Bruhn JG (October 2005). "Prehistoric peyote use: alkaloid analysis and radiocarbon dating of archaeological specimens of Lophophora from Texas". J Ethnopharmacol.
  5. PEYOTE (LOPHOPHORA WILLIAMSII) AND PLANTS CONFUSED WITH IT by Richard Evans , Harvard University (November 19, 1937) |
  6. Peyote: The Divine Cactus By Edward F. Anderson, Page 160


  1. 1717 CheMall OR052244
  2. 1717 CheMall OR146516
  3. 1717 CheMall OR194297
  4. A&J Pharmtech AJ-08069
  5. A&J Pharmtech AJ-143283
  6. abcr AB466401
  7. ACToR: Aggregated Computational Toxicology Resource 54-04-6
  8. Advanced Technology & Industrial 3580900
  9. AKos AKOS000277426
  10. ALK ALG00158506
  11. Angene AG-A-47573
  12. Angene AGN-PC-0786UH
  13. Ark Pharm, Inc. AK153291
  14. Aurora Fine Chemicals A00.555.223
  15. Aurora Fine Chemicals K02.874.567
  16. Bide Pharmatech BD167979
  17. BIND (no longer updated) 332
  18. Biosynth W-204256
  19. Biosynth Carbosynth FT55211
  20. Cambridge Chem CC167997
  21. CambridgeSoft Corporation 6182
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  24. ChemAdvisor OHS14045
  25. ChemAdvisor OHS14045
  26. ChemBank DivK1c_000984
  27. ChemBank KBio1_000984
  28. ChemBank NINDS_000984
  29. ChEMBL CHEMBL26687
  30. ChemDB 3967410
  31. ChemIDplus 000054046
  32. ChemIDplus 54046
  33. Chemspace CSC017304756
  34. ChemSynthesis 26966
  35. Collaborative Drug Discovery 41509
  36. DiscoveryGate 4076
  37. DSigDB d4ttd_9210
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  40. eMolecules 872968
  41. EPA DSSTox DTXCID40124794
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  43. FDA UNII - NLM RHO99102VC
  45. Fluorochem 456477
  46. iChemical EBD70994
  47. Jean-Claude Bradley Open Melting Point Dataset 21758
  48. KEGG C06546
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  101. Springer Nature Effect of deglycyrrhizinized liquorice on gastric acid secretion, histidine decarboxylase activity and serum gastrin level in the rat
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  3. PubChem National Center for Bio Informatics
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