MET

MET

MET

Psychoactive Research chemicals are new synthetic substances that are structurally similar to the original drug, while being functional analogs. Research on the effects of, and treatment for, abuse of these drugs is limited due to the fact that they’re fairly new and have avoided mainstream notice. Research chemicals do not have a lot of human consumption data, and thus harm-reduction and special care should be taken if choosing to ingest them.

Psychedelics are drugs which cause profound changes in a one’s perceptions of reality, otherwise known as hallucinations. While under the influence of hallucinogens, users might see images, hear sounds or feel sensations. These chemicals offer some of the most intense psychological experiences and care should be taken when ingesting them.

Experimental drugs have extremely limited human consumption data. There is not enough reliable information about this substance. This is most likely because the substance is is not very old. Information on these substances is limite and incomplete. Please be cautioned. Always practice harm reduction.

Disclaimer: Psychedelic drugs offer some of the most power and intense psychological experiences. Additionally these substances are illegal in many places. We understand that even though these substances are illegal, their use occurs frequently. We do not condone breaking of the law. By providing accurate information about these substances, we encourage the user to make responsible decisions and practice harm reduction.

Read the full disclaimer here.

Practice Harm Reduction. Proceed with Caution.

Description

MET

Also known as:

  • 1H-Indole-3-ethanamine, N-ethyl-N-methyl-[ACD/Index Name]
  • Methylethyltryptamine
  • N-Ethyl-2-(1H-indol-3-yl)-N-methylethanamin[German][ACD/IUPAC Name]
  • N-Ethyl-2-(1H-indol-3-yl)-N-methylethanamine[ACD/IUPAC Name]
  • N-Éthyl-2-(1H-indol-3-yl)-N-méthyléthanamine[French][ACD/IUPAC Name]
  • N-Methyl-N-ethyltryptamine
  • N-Methyl-N-Ethyltryptamine(MET)
  • 4KX1J1D3RD
  • AC1LGOFD
  • AGN-PC-04XNH4
  • AKOS015967217
  • ethyl[2-(1H-indol-3-yl)ethyl]methylamine
  • MFCD04088367
  • MolPort-002-799-637
  • N-ethyl-2-(1H-indol-3-yl)-N-methylethan-1-amine
  • N-ethyl-N-[2-(1H-indol-3-yl)ethyl]-N-methylamine
  • N-Ethyl-N-methyl-1H-indole-3-ethanamine

A rare psychedelic tryptamine, related to DMT and DET. Little information exists about the effects or pharmacology of this drug.

Summary

It is structurally related to DMT and is similarly unique among psychedelics due to its short-lived effects, rapid onset and progressive stages. The fumarate salt has been reported as being active via smoking/vaporization at 15-65 mg and orally at 80-110 mg. When smoked or vaporized it has been reported to produce effects similar to those of DMT with some distinct stylistic variations which include a more grounded headspace, stimulating physical effects, and reduced subjective intensity.

Very little data exists about the pharmacological properties, metabolism, and toxicity of MET, and it has a very brief history of human usage. Today, it is either used recreationally or as an entheogenic substance and has been exclusively distributed by online research chemical vendors since mid-2016. Due to its unstudied properties and effects, it is highly advised to approach this novel psychedelic substance with the proper precautions and harm reduction practices if choosing to use it.

History

Chemistry

MET

MET

Tryptamines share a core structure that comprises a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain.

Unlike DMT, which contains two methyl groups, MET contains groups of one methyl and one ethyl carbon chains bound to the terminal amine RN of its tryptamine backbone.

Common NameMethylethyltryptamine
Systematic nameMethylethyltryptamine
FormulaC_{13}H_{18}N_{2}
SMILESCCN(C)CCc1c[nH]c2c1cccc2
Std. InChiInChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
Std. InChiKeyFFEARJCKVFRZRR-BYPYZUCNSA-N
Avg. Mass202.2954 Da
Molecular Weight202.2954
Monoisotopic Mass202.147003 Da
Nominal Mass202
ChemSpider ID720502

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Dosing Guide

Oral
Light10-20mg
Common20-25mg
Strong25-30mg+

Duration

Oral
Onset60-90 minutes
Duration4-6 hours
After-effects1-6 hours

Interactions and Synergies

There are no existing interaction or synergy data for this drug.

General Information

Experiences
Oral
Vaporization
Come up
Dosage
EffectsEuphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.
After Effects
Avoid
Warning
Risks
Test Kits
Marguis Test Result
Tolerance
Detection
Half-life
Advice
Note
Note 2:
Note 3:

Effects

Pharmacological Effects

As with most psychedelic tryptamines, MET is thought to act principally as a 5-HT2A partial agonist. The psychedelic effects are believed to come from MET’s binding efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continue to remain elusive.

Subjective Effects

Physical Effects

Psychological Effects

Visual Effects

Enhancements

Suppressions

Distortions

Geometry

The visual geometry produced by this compound can be described as somewhat similar in appearance to that of DMT, 4-HO-MET and DET. It can be comprehensively described through its variations as intricate in complexity, abstract in form, equally synthetic and organic in style, structured in organization, extremely brightly lit and multicoloured in scheme, glossy in shading, equally sharp and soft in its edges, large in size, fast in speed, smooth in motion, equally rounded and angular in its corners, non-immersive in depth and consistent in intensity. The visuals have a contradictory natural and synthetic feel to them which is reminiscent of both LSD and psilocybin.

Hallucinatory states

Auditory Effects

Sensory Effects

Transpersonal Effects

It should be noted that these effects are the rarest and least reproducible those that can occur during a psychedelic experience. They are considered unique in that that simply taking more of the substance does not necessarily increase the chance they will occur, and are said to rely more on contextual factors such as the user's set and setting rather than the substance or dose itself. Their fullest manifestations are sometimes called "peak", "transcendent" or "transformative" experiences; however, they can still occur on a conceptual or cognitive level that can leave a lasting positive impact on the user.

Legal Status

Due to its relative obscurity, the possession and sale of MET is unscheduled in most countries.

  • Germany: MET is controlled under the NpSG (New Psychoactive Substances Act) as of July 18, 2019. Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.
  • New Zealand: MET is an analogue of DMT, so is a Class C controlled substance in New Zealand.
  • United Kingdom: MET is a Class A controlled substance in the UK under a generic clause originally added in 1977 that covers derivatives of tryptamine that are modified by alkyl substitution at the nitrogen atom of the tryptamine side chain.
  • United States: MET is unscheduled in the United States. However, it is likely that it would be considered a controlled substance analogue of DMT or DET, in which case, sales for human consumption or possession with the intent to ingest could be prosecuted under the Federal Analogue Act.

  • References

    1. "Anlage NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
    2. "Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes" (PDF). Bundesgesetzblatt Jahrgang 2019 Teil I Nr. 27 (in German). Bundesanzeiger Verlag. July 17, 2019. pp. 1083–1094. Retrieved January 1, 2020.
    3. "§ 4 NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
    4. "Schedule 1 Class A controlled drugs". "Reprint as at 13 August 2019: Misuse of Drugs Act 1975". Parliamentary Counsel Office. Retrieved January 7, 2020.
    5. "The Misuse of Drugs Act 1971 (Modification) Order 1977". The National Archives. July 26, 1977. Retrieved January 10, 2020.

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