Psychoactive Research chemicals are new synthetic substances that are structurally similar to the original drug, while being functional analogs. Research on the effects of, and treatment for, abuse of these drugs is limited due to the fact that they’re fairly new and have avoided mainstream notice. Research chemicals do not have a lot of human consumption data, and thus harm-reduction and special care should be taken if choosing to ingest them.
Psychedelics are drugs which cause profound changes in a one’s perceptions of reality, otherwise known as hallucinations. While under the influence of hallucinogens, users might see images, hear sounds or feel sensations. These chemicals offer some of the most intense psychological experiences and care should be taken when ingesting them.
Disclaimer: Psychedelic drugs offer some of the most power and intense psychological experiences. Additionally these substances are illegal in many places. We understand that even though these substances are illegal, their use occurs frequently. We do not condone breaking of the law. By providing accurate information about these substances, we encourage the user to make responsible decisions and practice harm reduction.
Practice Harm Reduction. Proceed with Caution.
Also known as:
ine, N,N-bis(1-meth[ACD/Index Name] ylethyl)-
- INDOLE, 3-(2-(DIISO
)ethyl]-N-isopropyl[German][ACD/IUPAC Name] -2-propanamin
)ethyl]-N-isopropyl[ACD/IUPAC Name] -2-propanamine
)éthyl]-N-isopropyl[French][ACD/IUPAC Name] -2-propanamine
tamine free base
tamine, free base
)ethyl]-N-(propan-2[ACD/IUPAC Name] -yl)propan-2-amine
A rare tryptamine psychedelic closely related to DMT, with the interesting property of having little visual hallucinations, but strong auditory effects.
It is a structural analog of DMT and related to various psychedelic tryptamines such as 4-HO-DiPT, 5-MeO-DiPT, and MiPT. The first human trials of DiPT were undertaken in 1975 by Alexander Shulgin, who would co-author and publish a paper detailing its synthesis and human psychopharmacology in 1981. A summary of the synthesis and reports of human use is included in Shulgin's 1997 book TiHKAL ("Tryptamines I Have Known And Loved").
It has been sold online as a research chemical. While most psychedelics are known for producing vivid visual distortions, DiPT’s effects are reported to be primarily auditory in nature. Anecdotal reports have described it causing a downward shift in perceived pitch and other unusual distortions.
It has been suggested that DiPT may have value in neurological research due to its unique effects on auditory perception. Additional subjective effects of DiPT include a body high, moderate euphoria, mild visuals, dizziness, and nausea. Very little data exists about the pharmacological properties, metabolism, and toxicity of DiPT, and it has a limited history of human use.
It is highly advised to use harm reduction practices if using this substance.
Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. DiPT also contains two isopropyl groups bound to the terminal amine RN of its tryptamine backbone.
Isopropyl groups are a three carbon (propyl) chain bound at the middle carbon to the chemical structure.
DiPT has substituted analogues such 5-MeO-DiPT. DiPT is analogous to DMT, containing two isopropyl groups bound at RN instead of the two methyl groups found in DMT.
|Avg. Mass||244.3752 Da|
|Monoisotopic Mass||244.193954 Da|
|DiPT Duration Data|
Interactions and Synergies
There are no existing interaction or synergy data for this drug.
|Effects||Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.|
|Marguis Test Result|
The psychedelic effects of DiPT are believed to come from its efficacy at the 5-HT2A receptor. However, the role of these interactions and how they result in the psychedelic experience remains subject to on-going scientific investigation.
- Spontaneous physical sensations
- Tactile enhancement
- Increased heart rate
- Increased blood pressure
- Excessive yawning
- Pupil dilation
The cognitive effects of DiPT are reportedly very lucid and clear-headed in comparison to most other tryptamines.
- Increased music appreciation - This effect is subjective and depends on the person and the perceived tunes.
- Analysis enhancement
- Ego dissolution
- Thought acceleration
The sensory effects of DiPT are mostly auditory, however may still produce visual effects, in a similar fashion to other serotonergic psychedelics, especially at higher dosages These effects can include:
- Drifting (melting, breathing, morphing and flowing)
- Color enhancement
- Depth perception distortions
- Geometry - The visual geometry produced by this compound can be described as somewhat similar in appearance to that of DMT.
There is much speculation as to the nature of DiPT's aural distortion. At lower dosages, it has been reported to have an effect similar to a flanging, or a phase shift. At medium and higher dosages, the effect of DiPT is typically a radical shift downward in perceived pitch. This shift also tends to be nonlinear in that the shift downwards varies in relation to the initial pitch, for example, higher pitches are not lowered as much as already low pitches. This can produce bizarre sounds and render music disharmonious or unrecognizable These auditory effects of DiPT are very apparent in their occurrence and exhibit a full range of effects which commonly includes:
- Auditory enhancement
- Auditory distortion
- Auditory hallucination
- Tinnitus - This is more common in quiet areas or is exaggerated whilst yawning. It does not necessarily hurt in the ears and the pitch and frequency are not as high and constant.
- Ear pressure - This effect is generally mild but has been painful in some cases.
- Florida: DiPT is a Schedule I controlled substance in the state of Florida. It is illegal to buy, sell, or possess.
- Alexander Shulgin. Pharmacology Notes I (The Shulgin Lab Books) (PDF). Erowid. p. 177.
- Shulgin, A. T.; Carter, M. F. (1980). "N, N-Diisopropyltryptamine (DIPT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT). Two orally active tryptamine analogs with CNS activity". Communications in psychopharmacology. 4 (5): 363–369. 0145-5699. OCLC 3012956. PMID 6949674.
- Shulgin, Alexander; Shulgin, Ann (1997). TiHKAL: The Continuation. United States: Transform Press. 0-9630096-9-9. OCLC 38503252.
- Shulgin & Shulgin 1997, p. 403–406.
- "Anlage NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
- "Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes" (PDF). Bundesgesetzblatt Jahrgang 2019 Teil I Nr. 27 (in German). Bundesanzeiger Verlag. July 17, 2019. pp. 1083–1094. Retrieved January 1, 2020.
- "§ 4 NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
- "Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem" (in Latvian). VSIA Latvijas Vēstnesis. November 10, 2005. Retrieved January 1, 2020.
- "Schedule 1 Class A controlled drugs". "Reprint as at 13 August 2019: Misuse of Drugs Act 1975". Parliamentary Counsel Office. Retrieved January 7, 2020.
- "Part I: Class A Drugs". "Misuse of Drugs Act 1971". UK Government. Retrieved January 7, 2020.
- The 2015 Florida Statutes | http://leg.state.fl.us/statutes/index.cfm?App_mode=Display_Statute&URL=0800-0899/0893/0893.html
- AKos AKOS015967146
- American Custom Chemicals Corp AAA0009562
- Angene AGN-PC-04XNH7
- Aurora Fine Chemicals K13.731.077
- BGS International BG04263315
- BGS International BG04263316
- Biosynth D-4230
- BOC Sciences 14780-24-6
- Cayman Chemical 11550
- Cayman Chemical 11550.0
- ChEBI CHEBI:48286
- ChemIDplus 014780246
- ChemIDplus 14780246
- Chemspace CSC016999132
- eMolecules 976823
- eNovation Chemicals K49773
- EPA DSSTox DTXCID7086295
- Erowid DIPT
- FDA UNII - NLM E352B01VMH
- iChemical EBD3059219
- LabNetwork LN01297361
- Laboratory Chemical Safety Summary 26903
- Mcule MCULE-5273479508
- Molport MolPort-001-784-320
- MuseChem R058683
- NIST Spectra mainlib_335456
- PIChemicals PI-33531
- PubChem 26903
- Rosewachem RW058428
- Springer Nature Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter
- Springer Nature Discriminative stimulus effects of N,N-diisopropyltryptamine
- Springer Nature Foxy methoxy: A new drug of abuse
- Springer Nature Hallucinogens in Drug Discrimination
- Springer Nature Metabolism and toxicological analyses of hallucinogenic tryptamine analogues being abused in Japan
- Springer Nature Prolonged delusional state triggered by repeated ingestion of aromatic liquid in a past 5-methoxy-N, N-diisopropyltryptamine abuser
- Springer Nature Simultaneous determination of tryptamine analogues in designer drugs using gas chromatographyu2013mass spectrometry and liquid chromatographyu2013tandem mass spectrometry
- Springer Nature The role of 5-HT2A, 5-HT2C and mGlu2 receptors in the behavioral effects of tryptamine hallucinogens N,N-dimethyltryptamine and N,N-diisopropyltryptamine in rats and mice
- VulcanChem VC283565
- Wikidata Q1984429
- Wikipedia Diisopropyltryptamine
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- PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
- Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
- PubChem National Center for Bio Informatics
- Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
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