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Also known as:

  • 1H-Indole-3-ethanamine, N,N-diethyl-[ACD/Index Name]
  • 1H-Indole-3-ethanamine, N,N-diethyl- (9CI)
  • 5-22-10-00050 (Beilstein Handbook Reference)[Beilstein]
  • D.E.T.
  • DET
  • Indole, 3-(2-(diethylamino)ethyl)-
  • N,N-Diethyl-2-(1H-indol-3-yl)ethanamin[German][ACD/IUPAC Name]
  • N,N-Diethyl-2-(1H-indol-3-yl)ethanamine[ACD/IUPAC Name]
  • N,N-Diéthyl-2-(1H-indol-3-yl)éthanamine[French][ACD/IUPAC Name]
  • 3-(2-Diethylaminoethyl)indole
  • CHEMBL142936
  • diethyl[2-(1H-indol-3-yl)ethyl]amine
  • diethyl-[2-(1H-indol-3-yl)ethyl]amine
  • Diethyl-[2-(1H-indol-3-yl)-ethyl]-amine
  • Oprea1_105894
  • tryptamine, N,N-diethyl

A surprisingly uncommon analogue of DMT with similar effects and reported oral activity without the aid of an MAOI.


It is extremely uncommon and has little history of human usage.





Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain.

DMT contains two ethyl groups CH2CH3- bound to the terminal amine RN of its tryptamine backbone.

DET has many substituted analogues such as 4-HO-DET (“ethocin”).

Common NameN,N-Diethyltryptamine
Systematic nameN,N-Diethyltryptamine
Std. InChiInChI=1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3
Avg. Mass216.322 Da
Molecular Weight216.322
Monoisotopic Mass216.162643 Da
Nominal Mass216
ChemSpider ID5865

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Dosing Guide



Onset1-5 minutes
Duration2-4 hours
After-effects1-6 hours

Interactions and Synergies

There are no existing interaction or synergy data for this drug.

General Information

Come up
DosageVaporized (using a 100% success method) Light: 15-25mg's Common: 30-50mg's Strong: 50mg+ Orally Light: 20-40mg's Common: 50-80mg's Strong: 80mg+
EffectsEuphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.
After Effects
Test Kits
Marguis Test Result
Note 2:
Note 3:


Pharmacological Effects

Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based on its structure and subjective effect similarities to other tryptamine psychedelics such as psilocin and DMT. With this in mind, DET is thought to act as an 5-HT2A partial agonist. Unlike DMT, the ethyl groups add protection against the monoamine oxidase enzyme system, allowing DET to be orally active, while DMT is not. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective Effects

Physical Effects

Psychological Effects

Visual Effects




Hallucinatory states

Auditory Effects

Sensory Effects

Transpersonal Effects

Legal Status

  • Germany: DET is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of January 24, 1974. It is illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license.
  • Italy: DET is a Schedule I controlled substance.
  • New Zealand: DET is a Class A controlled substance in New Zealand.
  • United Kingdom: DET is a Class A controlled substance.
  • United States: DET is a Schedule I controlled substance.

  • References

    1. Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology, 5(2), 63-67. doi:10.1007/BF03161089
    2. "Anlage I BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
    3. "Sechste Verordnung über die den Betäubungsmitteln gleichgestellten Stoffe" (PDF). Bundesgesetzblatt Jahrgang 1974 Teil I Nr. 6 (in German). Bundesanzeiger Verlag. January 23, 1974. pp. 97–98. Retrieved January 7, 2020.
    4. "§ 29 BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
    5. "Tabella I" (PDF) (in Italian). Ministero della Salute [Ministry of Health]. p. 8. Retrieved January 7, 2020.
    6. "Schedule 1 Class A controlled drugs". "Reprint as at 13 August 2019: Misuse of Drugs Act 1975". Parliamentary Counsel Office. Retrieved January 7, 2020.
    7. "Part I: Class A Drugs". "Misuse of Drugs Act 1971". UK Government. Retrieved January 7, 2020.
    8. "Controlled Substances: by CSA Schedule" (PDF). U.S. Department of Justice. August 21, 2019. p. 4. Retrieved January 7, 2020.


    1. ACToR: Aggregated Computational Toxicology Resource 61-51-8
    2. American Custom Chemicals Corp API0014206
    3. American Custom Chemicals Corp API0014346
    4. Angene AGN-PC-04XNLW
    5. Aurora Fine Chemicals K05.114.781
    6. BindingDB 50094676
    7. ChEMBL CHEMBL142936
    8. ChemDB 4514943
    9. ChemIDplus 000061518
    10. ChemIDplus 61518
    11. CSDeposition Service DB01460
    12. DiscoveryGate 6090
    13. DrugBank DB01460
    14. DSigDB d4ttd_7573
    15. eMolecules 976819
    16. EPA DSSTox DTXCID7031373
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    18. FDA UNII - NLM 916E8V4S2V
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    20. iChemical EBD3060168
    21. Jean-Claude Bradley Open Melting Point Dataset 16302
    22. LeadScope LS-82868
    23. NIAID 517294
    24. NIST Chemistry WebBook 4120394730
    25. NIST Spectra mainlib_246229
    26. NIST Spectra nist ri
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    54. ZINC ZINC01999162


    Information made possible with:

    1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
    2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
    3. PubChem National Center for Bio Informatics
    4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
    5. Wikipedia

    Additional APIs were used to construct this information. Thanks for ChemSpider, NCBI, PubChem etc.

    Data is constantly updated so please check back later to see if there is any more available information on this substance.