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5-MeO-MALT Also known as:

  • 1H-Indole-3-ethanamine, 5-methoxy-N-methyl-N-2-propen-1-yl-[ACD/Index Name]
  • N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-N-methyl-2-propen-1-amin[German][ACD/IUPAC Name]
  • N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-N-methyl-2-propen-1-amine[ACD/IUPAC Name]
  • N-[2-(5-Méthoxy-1H-indol-3-yl)éthyl]-N-méthyl-2-propén-1-amine[French][ACD/IUPAC Name]
  • N-[2-(5-methoxy-1H-indole-3-yl)ethyl]-N-methyl-prop-2-en-1-amine[ACD/IUPAC Name]

A new and uncommon psychedelic tryptamine related to 5-MeO-DALT. Little is known about it, but its effects are probably similar to other psychedelic tryptamines.




Common Name5-MeO-MALT
Systematic name5-MeO-MALT
Std. InChiInChI=1S/C15H20N2O/c1-4-8-17(2)9-7-12-11-16-15-6-5-13(18-3)10-14(12)15/h4-6,10-11,16H,1,7-9H2,2-3H3
Avg. Mass244.3321 Da
Molecular Weight244.3321
Monoisotopic Mass244.157562 Da
Nominal Mass244
ChemSpider ID58191434

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Dose Chart


Duration Chart

Onset5-30 minutes
Duration2-4 hours

Auditory Effects

Psychological Effects

Pharmacological Effects

5-Meo-DMT’s psychedelic effects are primarily believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. Specifically, this molecule shows high binding affinity for the 5-HT2A and 5-HT1A subtypes. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive. Additional mechanisms of action such as reuptake inhibition of neurotransmitters such as serotonin, noradrenaline and dopamine are also thought to be involved to an extent. This can result in 5-MeO-DMT becoming dangerously toxic when combined with MAOIs, RIMAs, SSRIs, stimulants or any substance which acts as a releasing agent or reuptake inhibitor of monoamine neurotransmitters. 5-MeO-DMT is O-demethylated by polymorphic cytochrome P450 2D6 (CYP2D6) to an active metabolite, bufotenin.

Physical Effects

The physical effects of 5-MeO-DMT can be broken down into several components which progressively intensify proportional to dosage. In comparison to its often relatively mild accompanying cognitive and visual effects, 5-MeO-DMT seems to have by far the most proportionally intense and overwhelming physical sensations found within the known psychedelic experience. These individual components are complex, overwhelming and seem to be equally capable of being interpreted as either extremely pleasurable and euphoric or uncomfortable and dysphoric.

Sensory Effects

  • Synaesthesia - In its fullest manifestation, this is a very rare and non-reproducible effect. Increasing the dosage can increase the likelihood of this occurring, but seems to only be a prominent part of the experience among those who are already predisposed to synaesthetic states.

Subjective Effects

Visual Effects

The visual effects of 5-MeO-DMT can be broken down into several components which progressively intensify proportional to dosage. In comparison to its consistently overwhelming and intense accompanying cognitive and physical effects, 5-MeO-DMT seems to have some of the most proportionally underwhelming visual effects found within the known varieties of the psychedelic experience.


The visual geometry that is present throughout this trip does not usually occur and in notable contrast to DMT, does not extend beyond level 7 at its highest state (though some experiences involving nonvisual 8b have been reported). It is vaguely similar to DMT although significantly smaller in size and more likely to manifest in darkness or without distractions. In terms of appearance, it can be comprehensively described through its variations as intricate in complexity, abstract in form, equally organic and digital in feel, structured in organization, brightly lit, multicoloured in scheme, glossy in shading, equal in sharp and soft edges, small in size, fast in speed, smooth in motion, equal in rounded and angular corners, immersive in-depth and consistent in its intensity. 5-MeO-DMT is unique in that in breakthrough doses, it uniquely tends to result in 8B Geometry over level 8A.


Information made possible with:

  1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
  2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
  3. PubChem National Center for Bio Informatics
  4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
  5. Wikipedia

Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.

Data is constantly updated so please check back later to see if there is any more available information on this substance.