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Description

2C-T-7 Also known as:

  • 2,5 Dimethoxy-4-(propylthio) phenethylamine
  • 2,5-dimethoxy-4-n-propylthiophenethylamine
  • 2,5-dimethoxy-4-propylthiophenethylamine
  • 2-[2,5-Dimethoxy-4-(propylsulfanyl)phenyl]ethanamin[German][ACD/IUPAC Name]
  • 2-[2,5-Dimethoxy-4-(propylsulfanyl)phenyl]ethanamine[ACD/IUPAC Name]
  • 2-[2,5-Diméthoxy-4-(propylsulfanyl)phényl]éthanamine[French][ACD/IUPAC Name]
  • 2C-T-7
  • Benzeneethanamine, 2,5-dimethoxy-4-(propylthio)-[ACD/Index Name]
  • 2-(2,5-Dimethoxy-4-(propylthio)phenyl)ethanamine
  • 2-(2,5-dimethoxy-4-propyl-3H-thiophen-2-yl)ethanamine
  • 2-(2,5-dimethoxy-4-propylsulfanylphenyl)ethanamine
  • 2-(2,5-dimethoxy-4-propylsulfanyl-phenyl)ethanamine
  • 2-(2,5-Dimethoxy-4-propylsulfanyl-phenyl)-ethylamine
  • 2-(2,5-dimethoxy-4-propylthiophenyl)ethylamine
  • 2,5-DIMETHOXY-4-(N)-PROPYLTHIOPHENETHYLAMINE
  • 2,5-DIMETHOXY-4-(PROPYLSULFANYL)PHENETHYLAMINE
  • 2-[2,5-dimethoxy-4-(propylthio)phenyl]ethanamine
  • 2-[2,5-dimethoxy-4-(propylthio)phenyl]ethylamine
  • '207740-26-9
  • 4-Propylthio-2,5-dimethoxyphenethylamine
  • MFCD03840819[MDL number]
  • phenethylamine, 2,5-dimethoxy-4-n-propylthio-
  • phenethylamine, 2,5-dimethoxy-4-propylthio-β-

A relatively uncommon psychedelic phenethylamine and possible MAOI. Long lasting, an possesses an unpredictable dosage curve. Questionable safety in combination with most things.

Summary

2C-T-7 was first synthesized by Alexander Shulgin and documented in his book PiHKAL ("Phenethylamines I Have Known and Loved"). It is a member of the 2C-x family of psychedelic phenethylamines, all of which were derived from the systematic modification of the mescaline molecule. In contrast to other members of the 2C-x family, 2C-T-7 has gained a reputation of being an unpredictable, dose-sensitive psychedelic capable of producing strong visual effects and an intense body load, which can manifest as a dangerous delirium in extreme cases.

Many reports indicate that the physical effects are too severe for inexperienced users or those with pre-existing medical conditions. This particular compound is part of the so-called “magical half-dozen” which refers to Shulgin’s self-rated most important phenethylamine compounds, all of which – with the exception of mescaline – he designed, synthesized and tested on himself. They can be found within the first book of PiHKAL, and are as follows: Mescaline, DOM, 2C-B, 2C-E, 2C-T-2 and 2C-T-7.

Chemistry

2C-T-7

2C-T-7

2C-T-7 is also substituted at R4 with a propyl thioether group. 2C-T-7 is analogous to 2C-T-2; the two differ by the length of the alkane chain in their thioether functional group.

Common Name2,5-dimethoxy-4-propylthiophenethylamine
Systematic name2,5-dimethoxy-4-propylthiophenethylamine
FormulaC_{13}H_{21}NO_{2}S
SMILESCCCSc1cc(c(cc1OC)CCN)OC
Std. InChiInChI=1S/C13H21NO2S/c1-4-7-17-13-9-11(15-2)10(5-6-14)8-12(13)16-3/h8-9H,4-7,14H2,1-3H3
Std. InChiKeyOLEVEPDJOFPJTF-UHFFFAOYSA-N
Avg. Mass255.3763 Da
Molecular Weight255.3763
Monoisotopic Mass255.129303 Da
Nominal Mass255
ChemSpider ID21106233

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Dose Chart

Oral
Light10-20mg
Common15-30mg
Strong30-40mg
Heavy40mg+

Duration Chart

Oral
Onset20-140 minutes
Duration6-12 hours
After-effects4-12 hours

Auditory Effects

Psychological Effects

The head space of 2C-T-7 is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.

Pharmacological Effects

2C-T-7’s psychedelic effects have been shown to come from its efficacy at the 5-HT2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive. With serious adverse effects seen on overdoses of this compound (potentially Serotonin Syndrome) and as the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor and many of the amphetamine-analogs of the 2C-T-x series are highly selective MAO-A inhibitors (with ALEPH-7 being one of the most potent), this substance is widely thought to also have MAOI effects.

Physical Effects

Subjective Effects

Visual Effects

Enhancements

Distortions

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 4-AcO-DMT or ayahuasca than that of LSD, 2C-B or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large, fast and smooth in motion, colorful in scheme, glossy in color, sharp in their edges and equally rounded and angular in their corners. It gives off a contradictory natural and synthetic feel with slightly more mystical and shamanic undertones in comparison to other phenethylamines. At higher dosages, they are equally likely to result in states of Level 8A visual geometry or Level 8B. There seems to be a visual geometry that is extremely similar to 2C-E and 2C-P and can be described as equal in intensity or complexity and equal in proportion to the accompanying cognitive and physical effects.

Hallucinatory states

2C-T-7 produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the phenethylamine family. These effects include:

Legal Status

  • Australia: In Australia, 2C-T-2 and 2C-T-7 are covered by the country's analog drug laws.
  • Austria: 2C-T-7 is illegal to possess, produce and sell under the SMG. (Suchtmittelgesetz Österreich)
  • Brazil: Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.
  • Canada: 2C-T-7 is considered Schedule III as it is a derivative of 2,5-dimethoxyphenethylamine.
  • China: As of October 2015 2C-T-7 is a controlled substance in China.
  • Germany: 2C-T-7 is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of July 1, 2001. It is illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license.
  • Latvia: 2C-T-7 is a Schedule I controlled substance in Latvia.
  • The Netherlands: The Netherlands was the first country in the world to ban 2C-T-7 after being sold in smart shops for a short period. After 2C-T-2 was first banned, 2C-T-7 quickly appeared on the market but was soon banned as well. 2C-T-7 is a list I drug of the Opium Law.
  • Sweden: The drug is Schedule I in Sweden. 2C-T-7 was first classified as a health hazard under the act "Lagen om förbud mot vissa hälsofarliga varor" (translated as "the Act on the Prohibition of Certain Goods Dangerous to Health") that made it illegal to sell or possess as of April 1, 1999.
  • Switzerland: Possession, production and sale is illegal.
  • United Kingdom: 2C-T-7 is a Class A drug in the United Kingdom as a result of the phenethylamine catch-all clause.
  • United States: On September 20, 2002, 2C-T-7 was classified as a Schedule I substance in the United States by an emergency ruling by the DEA. On March 18, 2004, the DEA published a final rule in the Federal Register which permanently placed 2C-T-7 in Schedule I.
  • Sources

    References

    1. Third Confirmed 2C-T-7 Death by Erowid Apr 10, 2001 | https://www.erowid.org/chemicals/2ct7/2ct7_death3.shtml
    2. A Reported 2C-T-7 Death by Erowid July 2003 | https://www.erowid.org/chemicals/2ct7/2ct7_death1.shtml
    3. Second Reported 2C-T-7 Death by Erowid Apr 2, 2001 | https://www.erowid.org/chemicals/2ct7/2ct7_death2.shtml
    4. Zimmerman, M.M., “The identification of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7).” Microgram, Vol. XXXIV, No. 7, July 2001, pp. 169-173.
    5. https://erowid.org/library/books_online/pihkal/pihkal.shtml | PiHKAL
    6. https://erowid.org/library/books_online/pihkal/pihkal.shtml | PiHKAL
    7. http://isomerdesign.com/PiHKAL/read.php?id=43
    8. Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats | http://link.springer.com/article/10.1007/s00213-005-0009-4
    9. Wagmann, Lea; Brandt, Simon D.; Stratford, Alexander; Maurer, Hans H.; Meyer, Markus R. (2019). "Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases". Drug Testing and Analysis. 11 (2): 318–324. :10.1002/dta.2494.  1942-7603.
    10. https://www.ncbi.nlm.nih.gov/pubmed/15801832
    11. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.689.281&rep=rep1&type=pdf
    12. Curtis, B., Kemp, P., Harty, L., Choi, C., & Christensen, D. (2003). Postmortem identification and quantitation of 2, 5-dimethoxy-4-n-propylthiophenethylamine using GC-MSD and GC-NPD. Journal of analytical toxicology, 27(7), 493-498.
    13. 2C-T-7 Overdoses & Delirium | https://www.erowid.org/chemicals/2ct7/2ct7_effects.shtml#overdose
    14. Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors:  Biological Activities, CoMFA Analysis, and Active Site Modeling | http://pubs.acs.org/doi/abs/10.1021/jm0493109
    15. http://portal.anvisa.gov.br/documents/10181/3115436/(1)RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7
    16. Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28
    17. "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.
    18. "Fünfzehnte Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften" (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
    19. "Anlage I BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    20. "§ 29 BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    21. Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086
    22. http://www.lakemedelsverket.se/upload/lvfs/LVFS_2004-3.pdf
    23. http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html
    24. United Kingdom. (1977). Misuse of Drugs Act 1971 (S.I. 1977/1243). London: The Stationery Office Limited. Retrieved July 5, 2017, from http://www.legislation.gov.uk/uksi/1977/1243/made

    Information made possible with:

    1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
    2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
    3. PubChem National Center for Bio Informatics
    4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
    5. Wikipedia

    Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.

    Data is constantly updated so please check back later to see if there is any more available information on this substance.