Psychedelic Research Chemicals or RC Chems are new synthetic substances which are structurally similar to the original drug, while being functional analogs. Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history.
Psychedelics are substances (natural or laboratory made) which cause profound changes in a one’s perceptions of reality. While under the influence of hallucinogens, users might hallcuniate visually and auditorily.
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2C-B-FLY Also known as:
etrahydrofuro[2,3-f[German][ACD/IUPAC Name] ]benzofuran-4-yl )ethanamin
tetrahydrobenzo[1,2 -b:4,5-b']difuran-4 -yl)ethanamine
tetrahydrofuro[2,3-[ACD/IUPAC Name] f]benzofuran-4-y l)ethanamine
tétrahydrofuro[2,3-[French][ACD/IUPAC Name] f]benzofuran-4-y l)éthanamine
RAHYDROBENZO(1,2-B: 4,5-B')DIFURAN-4-ET HANAMINE
difuran-4-ethanamin[ACD/Index Name] e, 8-bromo-2,3,6,7- tetrahydro-
tetrahydrofuro[2,3- f]benzofuran-8-yl)e thanamine
tetrahydrobenzo[1,2 -b:4,5-b]difuran-4- yl)ethanamine
tetrahydrobenzo-[1, 2-b:4,5-b']difuran- 4-yl)ethanamine
tetrahydrobenzo[1,2 -b:4,5-b`]difuran-4 -yl)ethanamine
tetrahydro-benzo[1, 2-b;4,5-b']difuran- 4-yl)-ethylamine
tetrahydrobenzofuro [5,6-b]furan-4-yl)e thanamine hydrochlo ride
tetrahydrofuro[2,3-[ACD/IUPAC Name] f]benzofurane-4- yl)ethanamine
zo-dihydro-difurane[ACD/IUPAC Name] -ethylamine
Psychedelic phenethylamine that is the dihydrodifuran analog of 2C-B.
Reports have characterized its effects profile as possessing features of 2C-B, mescaline and MDA, with a duration of 6–8 hours (or up to 12 hours in larger doses). 2C-B-FLY is a derivative of the 2C-x family of psychedelic phenethylamines, specifically 2C-B, of which it significantly differs from in terms of its potency, metabolism, and potential toxicity. It was first synthesized by Aaron P.
Monte in 1996. Around 2005, 2C-B-FLY appeared and gained some popularity in the online research chemicals market before largely disappearing in October 2009, when a batch of Bromo-DragonFLY was accidentally mislabeled as 2C-B-FLY (Bromo-DragonFLY is dosed in micrograms, where 2C-B-FLY is dosed in milligrams) led to two deaths as a result of taking overdoses of Bromo-DragonFLY meant to be effective doses for 2C-B-FLY. This event led to its immediate withdrawal until around 2016, when it resurfaced on the market again.
Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-B-FLY, and it has little history of human usage. It has no documented history of being sold on the streets and is commercially distributed through online research chemical vendors. Due to its high potency and sensitive dose-response, many reports also indicate that the effects of this substance should not be seen as a simple substitute for 2C-B.
It is highly advised to approach this potent, long-lasting, and unpredictable hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it.
In a 2007 MAPS newsletter interview, Ann Shulgin revealed that 2C-B-FLY as one of her favorite psychedelic substances while also acknowledging the high variability in responses it seemed to display.
I said often, too often, that something called 2CB Fly (sic) was absolutely great for me. To me, it’s the loveliest thing, especially for eroticism. But I found out that it’s not interesting to anybody else.— Ann Shulgin
I realized that having said that, I was putting things in motion. The Internet was full of 2CB Fly (sic), and people were asking about it and I thought “uh-oh.” It turned out that it’s a disappointment to most other people.
2C-B-FLY features a phenyl ring bound to an amino (NH2) group through an ethyl chain and contains a bromine atom attached to carbon R4 of the phenyl ring. It is an atypical psychedelic phenethylamine which is closely analogous to 2C-B; it is the dihydrofuran analog to 2C-B, where it incorporates the methoxy groups bound to R2 and R5 of 2C-B into five-member dihydrofuran rings fused to the central benzene ring. 2C-B-FLY belongs to a group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” tetrahydrofuran rings fused on the opposite sides of the central benzene ring.
The incorporation of the two methoxy groups into the 5 member rings fixes them into the optimum position for binding to the receptors they interact with resulting in an increase in potency compared to the compound’s non-rigid counterpart 2C-B.
|Avg. Mass||284.1491 Da|
|Monoisotopic Mass||283.020782 Da|
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|2C-B-FLY Duration Data|
- Information on Reported Deaths Related to 2C-B-FLY | https://www.erowid.org/chemicals/2cb_fly/2cb_fly_death1.shtml
- Talaie, H.; Panahandeh, R.; Fayaznouri, M. R.; Asadi, Z.; Abdollahi, M. (2009). "Dose-independent occurrence of seizure with tramadol". Journal of Medical Toxicology. 5 (2): 63–67. :10.1007/BF03161089. 1556-9039.
- Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors: Biological Activities, CoMFA Analysis, and Active Site Modeling | http://pubs.acs.org/doi/abs/10.1021/jm0493109
- Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28
- "Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe" (PDF) (in German). Bundesanzeiger Verlag. Retrieved December 11, 2019.
- "Anlage NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 11, 2019.
- "§ 4 NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 11, 2019.
- Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted
- Abblis Chemicals AB1006818
- AKos AKOS015950994
- Alichem A019106609
- Amadis Chemical A812382
- Angene AGN-PC-0QBDK6
- Ark Pharm, Inc. AK327320
- Aurora Fine Chemicals A24.548.152
- Aurora Fine Chemicals K18.962.873
- BGS International BG00992990
- BindingDB 50052339
- BLDpharm BD18943
- ChEMBL CHEMBL101189
- ChemIDplus 178557216
- ChemIDplus 733720951
- ChemShuttle 131866
- Chemspace CSC015193111
- EPA DSSTox DTXCID0093001
- Erowid 2C-B-Fly
- FDA UNII - NLM Z1T18Z40OT
- LabNetwork LN02189463
- Laboratory Chemical Safety Summary 10265873
- Mcule MCULE-8907136377
- MuseChem R052417
- PubChem 10265873
- SORD SST0025433
- SORD SST0025433
- Thomson Pharma 00536910
- VulcanChem VC245489
- Wikidata Q4633042
- Wikipedia 2C-B-FLY
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- PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
- Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
- PubChem National Center for Bio Informatics
- Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.
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