Psychedelic Research Chemicals or RC Chems are new synthetic substances which are structurally similar to the original drug, while being functional analogs. Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history.
Psychedelics are substances (natural or laboratory made) which cause profound changes in a one’s perceptions of reality. While under the influence of hallucinogens, users might hallcuniate visually and auditorily.
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2C-T-2 Also known as:
hylthio) phenethyla mine
)-2,5-dimethoxyphen[German][ACD/IUPAC Name] yl]ethanamin
)-2,5-dimethoxyphen[ACD/IUPAC Name] yl]ethanamine
)-2,5-diméthoxyphén[French][ACD/IUPAC Name] yl]éthanamine
4-(ethylthio)-2,5-d[ACD/Index Name] imethoxy-
ylthiophenethyl ami ne HCl
- MFCD03840818[MDL number]
- phenethylamine, 2,5
An unusual psychedelic with similar effects to 2C-B and a slightly longer duration, but maligned because of some deaths in the 2000s. Also similar to 2c-t-7, but with a shorter duration. Potentially unsafe with stimulants and empathogens.
It is a member of the 2C-x family of psychedelic phenethylamines, all of which were derived from the systematic modification of the mescaline molecule. 2C-T-2 was first synthesized and tested for activity in humans by Alexander Shulgin in 1981 and described in his 1991 book PiHKAL ("Phenethylamines I Have Known and Loved"). It is a member of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine-derived compounds, all of which except mescaline he developed and synthesized himself.
They are found within the first book of PiHKAL, and are as follows: mescaline, DOM, 2C-B, 2C-E, 2C-T-2 and 2C-T-7. Anecdotal reports generally characterize 2C-T-2 as a highly dose sensitive psychedelic known for its open headspace and unpredictable body load. Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-T-2, and it has a relatively short history of human usage.
Many reports also indicate that its physical effects may be too severe for those who are not already experienced with psychedelics or suffer from pre-existing physical conditions. It is highly advised to approach this hallucinogenic substance with the proper amount of precaution and harm reduction practices if using it.
Following the initial positive results found by Shulgin's research group, a more formal study was carried out by psychedelic psychotherapy pioneer Myron J. Stolaroff who was interested in evaluating the potential use of 2C-T-2 in psychotherapy. Based on the experiences of forty participants in the study who took 2C-T-2, Stolaroff compared the effects favorably to MDMA, describing it as more emotionally opening and permitting a wider exploration of feelings and thoughts.
2C-T-2 belongs to the 2C family of phenethylamines which contain methoxy functional groups CH3O- attached to carbons R2 and R5 of the benzene ring.
2C-T-2 is also substituted at R4 with an ethyl thioether group. 2C-T-2 is a close structural analogue of 2C-T-7; the two differ by the length of the alkane chain in their thioether functional group.
|Avg. Mass||241.3498 Da|
|Monoisotopic Mass||241.113647 Da|
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|2C-T-2 Duration Data|
- Shulgin, Alexander. "Pharmacology Lab Notes #4". Lafayette, CA. (1981-1982). p474 (Erowid.org) | https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebook4_searchable.pdf
- Shulgin, A., & Shulgin, A. (1991). IsomerDesign: "PiHKAL" - #33 - 2C-I. Retrieved Jan 22, 2018.
- Shulgin, A., & Shulgin, A. (1991). Erowid Online Books: "PIHKAL" - The Chemical Story. Retrieved April 14, 2017.
- Stolaroff, MJ; Wells, C. Preliminary results with new psychoactive agents 2C-T-2 and 2C-T-7. In Jahrbuch für Ethnomedizin und Bewußtseinsforschung (Yearbook of Ethnomedicine and the Study of Consciousness); Rätsch, C; Baker, J, Eds., 1993; Vol. 2, pp 99–117. (MAPS.org) | http://www.maps.org/images/pdf/1993_stolaroff_1.pdf
- Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors: Biological Activities, CoMFA Analysis, and Active Site Modeling | http://pubs.acs.org/doi/abs/10.1021/jm0493109
- Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28
- "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.
- "Zwölfte Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften" (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
- "Anlage I BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
- "§ 29 BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
- Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086
- United Kingdom. (1977). Misuse of Drugs Act 1971 (S.I. 1977/1243). London: The Stationery Office Limited. Retrieved July 5, 2017, from http://www.legislation.gov.uk/uksi/1977/1243/made
- 1717 CheMall OR009135
- AChemo AC-28266
- AKos AKOS015888164
- Amadis Chemical A814870
- American Custom Chemicals Corp CHM0008075
- Aurora Fine Chemicals A14.515.224
- Aurora Fine Chemicals K18.914.989
- Boerchem BC204825
- ChEMBL CHEMBL339223
- ChemIDplus 207740247
- eMolecules 977250
- EPA DSSTox DTXCID3097341
- Erowid 2-C-T-2
- FDA UNII - NLM WPS2KSX2TJ
- iChemical EBD46652
- Jalor-Chem I01-0999
- Laboratory Chemical Safety Summary 12074193
- Labseeker SC-19947
- Mcule MCULE-1874529442
- NIST Spectra mainlib_378824
- Novochemy NC-2562
- PubMed 14643503
- PubMed 15522711
- PubMed 16041763
- PubMed 16325192
- Rosewachem RW063430
- Sinova SL-00747
- Springer Nature
- Springer Nature Cross-reactivities of 39 new amphetamine designer drugs on three abuse drugs urinary screening tests
- Springer Nature Cross-reactivities of 41 new amphetamine designer drugs to EMIT?? immunoassays
- Wikidata Q2443432
- Wikipedia 2C-T-2
- Wolves Chemical EBD46652
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- PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
- Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
- PubChem National Center for Bio Informatics
- Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.
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